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Ro 60-0175

CAS No. 169675-08-5

Ro 60-0175 ( Ro 600175 )

产品货号. M12587 CAS No. 169675-08-5

Ro 60-0175 is a potent, selective 5-HT2C receptor agonist.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2130 有现货
10MG ¥3418 有现货
25MG ¥5581 有现货
50MG ¥7946 有现货
100MG ¥10935 有现货
500MG ¥21708 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Ro 60-0175
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Ro 60-0175 is a potent, selective 5-HT2C receptor agonist.
  • 产品描述
    Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively; induces hypolocomotion in rats at doses greater than 0.5 mg/kg s.c.; (0.3 and 1 mg/kg s.c.) simultaneously reduces both unpunished and punished lever pressing, a profile consistent with sedation, induces sedative-like responses via 5-HT(2C) receptor activation in vivo.
  • 同义词
    Ro 600175
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    5-HT Receptor
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    169675-08-5
  • 分子量
    226.68
  • 分子式
    C11H12ClFN2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC(CN1C=CC2=CC(=C(C=C21)Cl)F)N.C(=CC(=O)O)C(=O)O
  • 化学全称
    1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (S)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Damjanoska KJ, et al. J Pharmacol Exp Ther. 2003 Mar;304(3):1209-16.
2. Vickers SP, et al. Br J Pharmacol. 2000 Jul;130(6):1305-14.
3. Kennett G, et al. Eur J Pharmacol. 2000 Jan 10;387(2):197-204.
4. Jenck F, et al. Eur Neuropsychopharmacol. 1998 Aug;8(3):161-8.
产品手册
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